The Fruits of Our Labor
Expect the unexpected in research. Each project the Košmrlj's Group works on comes with both unforeseeable challenges and opportunities. Many of the papers we’ve published were born out of experiments performed on the fly or purely for curiosity's sake. Check out the list of our publications below, and don’t hesitate to contact us for more information.
Publications
2016-present
2023
Elucidating the reaction mechanism of a palladium-palladium dual catalytic process through kinetic studies of proposed elementary steps
Anže Ivančič, Janez Košmrlj and Martin Gazvoda
Inversion Theory Leveling as a New Methodological Approach to Antioxidant Thermodynamics: A Case Study on Phenol
Nikola Stamenković, Janez Cerkovnik and Nataša Poklar Ulrih
2022
Sustainable and Selective Modern Methods of Noble Metal Recycling
Anže Zupanc, Joseph Install, Marjan Jereb and Timo Juhani Repo
Deuterated Drugs and Biomarkers in the COVID-19 Pandemic
Ross D. Jansen-van Vuuren, Luka Jedlovčnik, Janez Košmrlj, Thomas E. Massey and Volker Derdau
ACS Omega 2022, 7, 41840–41858
Palladium-Mediated Incorporation of Carboranes into Small Molecules, Peptides, and Proteins
Martin Gazvoda, Heemal H. Dhanjee, Jacob Rodriguez, Joseph S. Brown, Charlotte E. Farquhar, Nicholas L. Truex, Andrei Loas, Stephen L. Buchwald and Bradley L. Pentelute
Synthesis of [2H5]baricitinib via [2H5]ethanesulfonyl
chloride
Ross D. Jansen-van Vuuren and Rahul Vohra
Electrical Response of Poly(N‑[3-(dimethylamino)Propyl]
Methacrylamide) to CO2 at a Long Exposure Period
Zahra Shahrbabaki, Farshad Oveissi, Syamak Farajikhah, Mohammad B. Ghasemian, Ross D. Jansen-van Vuuren, Philip G. Jessop, Jimmy Yun, Fariba Dehghani, and Sina Naficy
Design, Synthesis and Evaluation of Fused Bicyclo[2.2.2]octene as a Potential Core Scaffold for the Non-Covalent Inhibitors of SARS-CoV-2 3CLpro Main Protease
Barbara Herlah, Andrej Hoivik, Luka Jamšek, Katja Valjavec, Norio Yamamoto, Tyuji Hoshino, Krištof Kranjc and Andrej Perdih
Copper-Catalyzed Azide–Alkyne Cycloaddition of Hydrazoic Acid Formed In Situ from Sodium Azide Affords 4-Monosubstituted-1,2,3-Triazoles
Dominik Jankovič, Miha Virant and Martin Gazvoda
J. Org. Chem. 2022, 87, 4018–4028
The journal's top 20 Most-read Article in February and March 2022
The journal's top 20 Most-read Article in Year 2022
Iodine-Catalysed Dissolution of Elemental Gold in Ethanol
Anže Zupanc, Eeva Heliövaara, Karina Moslova, Aleksi Eronen, Marianna Kemell, Črtomir Podlipnik, Marjan Jereb and Timo Juhani Repo
2021
Iridium Azocarboxamide Complexes: Variable Coordination Modes, C–H Activation, Transfer Hydrogenation Catalysis, and Mechanistic Insights
Shubhadeep Chandra, Ola Kelm, Uta Albold, Arijit Singha Hazari, Damijana Urankar, Janez Košmrlj and Biprajit Sarkar
Utilization of Plant-Based Wastes for a Sustainable Preparation of Xanthophyll Esters via Acid Anhydrides Using β-Pinene as a Bio-Derived Solvent
Valentina Metličar, Krištof Kranjc and Alen Albreht
ACS Sustainable Chem. Eng. 2021 9, 10651–10661
The journal's top 20 Most-read Article for the previous 12 months
Comparison of analytical methods for antibody conjugates with application in nuclear imaging – Report from the trenches
Irene V. J. Feiner, Luka Rejc, Jordi Llop, et al.
Reactivity of substrates with multiple competitive reactive sites toward NBS under neat reaction conditions promoted by visible light
Blaž Grjol and Marjan Jereb
Longitudinal evaluation of a novel BChE PET tracer as an early in vivo biomarker in the brain of a mouse model for Alzheimer disease
Luka Rejc, Jordi Llop, et al.
One-Pot Synthesis of N-Iodo Sulfoximines from Sulfides
Anže Zupanc and Marjan Jereb
J. Org. Chem. 2021, 86, 5991–6000
The journal's top 20 Most-read Article in April 2021
Featured on the Cover
Catalytic Approach to Diverse α‐Aminoboronic Acid Derivatives by Iridium‐Catalyzed Hydrogenation of Trifluoroborate‐Iminiums
Andrej Šterman, Janez Košmrlj, Nina Žigart, Stanislav Gobec, Izidor Sosič and Zdenko Časar
Synthesis of 13N‐ and 15O‐Labeled Radiopharmaceuticals
Krishna R. Pulagam, Vanessa Gómez‐Vallejo, Fernando López‐Gallego, Luka Rejc and Jordi Llop
Book Chapter in Handbook of Radiopharmaceuticals: Methodology and Applications, 2nd Edition
Eds: Michael R. Kilbourn, Peter J. H. Scott, Wiley, 2021
Swarming behavior and in vivo monitoring of enzymatic nanomotors within the bladder
Sci. Robot. 2021, 6, eabd2823
Ana C. Hortelao, Cristina Simó, Luka Rejc, Tania Patiño, Jordi Llop, Samuel Sánchez, et al.
Pre-targeting with ultra-small nanoparticles: boron carbon dots as drug candidates for boron neutron capture therapy
Irene V. J. Feiner, Krishna R. Pulagam, Kepa B. Uribe, Rossana Passannante, Cristina Simó, Kepa Zamacola, Vanessa Gómez-Vallejo, Natalia Herrero-Álvarez, Unai Cossío, Zuriñe Baz, María M. Caffarel, Charles H. Lawrie, Danielle J. Vugts, Luka Rejc and Jordi Llop
Synthesis and Biochemical Evaluation of Warhead-Decorated Psoralens as (Immuno)Proteasome Inhibitors
Eva Shannon Schiffrer, Matic Proj, Martina Gobec, Luka Rejc, Andrej Šterman, Janez Mravljak, Stanislav Gobec and Izidor Sosič
Synthesis of Hydrazinylpyridines via Nucleophilic Aromatic Substitution and Further Transformation to Bicyclo[2.2.2]octenes Fused with Two N-Aminosuccinimide Moieties
An analysis of Electrophilic Aromatic Substitution: A “complex approach”
Nikola Stamenković, Nataša Poklar Ulrih and Janez Cerkovnik
Database Independent Automated Structure Elucidation of Organic Molecules Based on IR, 1H NMR, 13C NMR, and MS Data
Matevž Pesek, Andraž Juvan, Jure Jakoš, Janez Košmrlj, Matija Marolt and Martin Gazvoda
J. Chem. Inf. Model. 2021,61, 756–763
The journal's top 20 Most-read Article in January, February, March and April 2021
Featured on the Cover
A convenient approach to arenediazonium tosylates
Mateja Mihelač, Ana Siljanovska and Janez Košmrlj
2020
NaSH-HCl mediated reduction of sulfoxides into sulfides under organic solvent-free reaction conditions
Anže Zupanc and Marjan Jereb
Four Different Crystalline Products from One Reaction: Unexpected Diversity of Products of the CuCl2 Reaction with N-(2-Pyridyl)thiourea
Sara Tomšič, Janez Košmrlj and Andrej Pevec
Supramolecular Diversity of Oxabicyclo[2.2.2]octenes Formed between Substituted 2H-Pyran-2-ones and Vinyl-Moiety-Containing Dienophiles
Krištof Kranjc, Amadej Juranovič, Marijan Kočevar and Franc Perdih
Oral Treatment with Iododiflunisal Delays Hippocampal Amyloid-β Formation in a Transgenic Mouse Model of Alzheimer’s Disease: A Longitudinal in vivo Molecular Imaging Study
Luka Rejc, Vanessa Gómez-Vallejo, Xabier Rios, Unai Cossío, Zuriñe Baz, Edurne Mujica, Tiago Gião, Ellen Y. Cotrina, Jesús Jiménez-Barbero, Jordi Quintana, Gemma Arsequell, Isabel Cardoso and Llop, Jord
One pot synthesis of trifluoromethyl aryl sulfoxides by trifluoromethylthiolation of arenes and subsequent oxidation with hydrogen peroxide
Monika Horvat, Gregor Kodrič, Marjan Jereb and Jernej Iskra
Designing Homogeneous Copper-Free Sonogashira Reaction through a Prism of Pd–Pd Transmetalation
Bruno A. Martek, Martin Gazvoda, Damijana Urankar and Janez Košmrlj
Org. Lett. 2020, 22, 4938−4943
Featured on the Cover
The journal's top 20 Most-read Article in May, June, July, and August 2020
The journal's top 20 Most-read Article for the previous 12 months
Highlighted in Organic Chemistry Portal
Pyridine Wingtip in [Pd(Py-tzNHC)2]2+ Complex Is a Proton Shuttle in the Catalytic Hydroamination of Alkynes
Miha Virant, Mateja Mihelač, Martin Gazvoda, Andrej E. Cotman, Anja Frantar, Balazs Pinter and Janez Košmrlj
Ozone as a Pretreatment Method for Antibiotic Contaminated Wastewater and Sludge
Igor Boševski, Gabriela Kalčikova, Janez Cerkovnik and Andreja Žgajnar Gotvajn
Radiochemistry; A useful tool in the ophthalmic drug discovery
Krishna Reddy Pulagam, Vanessa Gómez-Vallejo, Jordi Llop and Luka Rejc
The Effect of the Methyl and Ethyl Group of the Acrylate Precursor in Hybrid Silane Coatings Used for Corrosion Protection of Aluminium Alloy 7075-T6
Damir Hamulić, Peter Rodič, Matic Poberžnik, Marjan Jereb, Janez Kovač and Ingrid Milošev
Preparation of Quinoline-2,4-dione Functionalized 1,2,3-Triazol-4-ylmethanols, 1,2,3-Triazole-4-carbaldehydes and 1,2,3-Triazole-4-carboxylic Acids
David Milićević, Roman Kimmel, Damijana Urankar, Andrej Pevec, Janez Košmrlj and Stanislav Kafka
Scalable Synthesis of Salt-free Quaternary Ammonium Carboxylate Catanionic Surfactants
Žiga Medoš, Miha Virant, Urša Štanfel, Boštjan Žener, Janez Košmrlj and Marija Bešter-Rogač
Acta Chim. Slov. 2020, 67, 270–275
2019
Arylation of Click Triazoles with Diaryliodonium Salts
Miha Virant and Janez Košmrlj
Half-Sandwich Ir(III) and Os(II) Complexes of Pyridyl-Mesoionic Carbenes as Potential Anticancer Agents
Juran Kralj, Aljoša Bolje, Darija Stupin Polančec, Ivana Steiner, Tena Gržan, Ana Tupek, Nikolina Stojanović, Stephan Hohloch, Damijana Urankar, Maja Osmak, Biprajit Sarkar, Anamaria Brozovic and Janez Košmrlj
Organometallics 2019, 38, 4082–4092
Featured on the Cover
Listed among the journal's top "20 Most read articles in November and December 2019"
The Radiopharmaceutical Chemistry of Nitrogen-13 and Oxygen-15
Vanessa Gómez-Vallejo, Luka Rejc, Fernando López-Gallego and Jordi Llop
Book Chapter in Radiopharmaceutical Chemistry
Eds: Jason S. Lewis, Albert D. Windhorst, Brian M. Zeglis, Springer 2019
1H−15N HMBC NMR as a tool for rapid identification of isomeric azaindoles: the case of 5F-MDMB-P7AICA
Bruno Aleksander Martek, Mateja Mihelač, Martin Gazvoda, Miha Virant, Damijana Urankar, Marko Krivec, Tomaž Gostič, Brigita Nemec, Bojana Koštrun, Mojca Janežič, Sonja Klemenc and Janez Košmrlj
3-(5-Amino-1,2,4-triazole)-1,2,4-oxadiazole: A new biheterocyclic scaffold for the synthesis of energetic materials
Lovel Kukuljan and Krištof Kranjc
Polynuclear oxomolybdates(VI): Products of inadvertent oxidation of molybdenum(V) species
Barbara Modec and Janez Košmrlj
The Value of In Vitro Binding as Predictor of In Vivo Results: A Case for [18F]FDDNP PET
Graham B. Cole, Nagichettiar Satyamurthy, Jie Liu, Koon-Pong Wong, Gary W. Small, Sung-Cheng Huang, Janez Košmrlj, Jorge R. Barrio and Andrej Petrič
2018
Negishi coupling reactions with [11C]CH3I: a versatile method for efficient 11C–C bond formation
Luka Rejc, Vanessa Gómez-Vallejo, Jesús Alcázar, Nerea Alonso, José Ignacio Andrés, Ana Arrieta, Fernando P. Cossío and Jordi Llop
Mechanism of copper-free Sonogashira reaction operates through palladium-palladium transmetallation
Martin Gazvoda, Miha Virant, Balazs Pinter and Janez Košmrlj
Nature Communications 2018, 9, 4814
Featured in Nature Communications Editors' Highlights
Versatile Coordination of Azocarboxamides: Redox-Triggered Change of the Binding Chelate in Ruthenium Complexes
Johannes Klein, Julia Beerhues, David Schweinfurth, Margarethe van der Meer, Martin Gazvoda, Goutam Kumar Lahiri, Janez Košmrlj and Biprajit Sarkar
Chem. Eur. J. 2018, 24, 18020–18031
Rated as Hot Paper
Systematic Evaluation of 2‑Arylazocarboxylates and 2‑Arylazocarboxamides as Mitsunobu Reagents
Daisuke Hirose, Martin Gazvoda, Janez Košmrlj and Tsuyoshi Taniguchi
J. Org. Chem. 2018, 83, 4712−4729
Featured in Organic Chemistry Portal
Highlighted in Organic Chemistry Portal
En Route to 2‑(Cyclobuten-1-yl)-3-(trifluoromethyl)‑1H‑indole
Martin Gazvoda, Marko Krivec, Zdenko Časar and Janez Košmrlj
Structural stabilization and characterization of active peroxo species on TiO2-nanotube based materials in mild catalytic wet peroxide oxidation process
Nina Drašinac Pajić, Petar Djinović, Goran Dražić, Jože Grdadolnik, Primož Šket, Janez Cerkovnik and Albin Pintar
Diversification of trifluoromethylthiolation of aromatic molecules with derivatives of trifluoromethanesulfenamide
Monika Horvat, Marjan Jereb and Jernej Iskra
Synthesis of Bis(1,2,3-Triazole) Functionalized Quinoline-2,4-Diones
David Milićević, Roman Kimmel, Martin Gazvoda, Damijana Urankar, Stanislav Kafka and Janez Košmrlj
Seasonal and spatial variations in the occurrence, mass loadings and removal of compounds of emerging concern in the Slovene aqueous environment and environmental risk assessment
Marjeta Česen, David Heath, Marko Krivec, Janez Košmrlj, Tina Kosjek and Ester Heath
Synthesis and in vitro investigation of halogenated 1,3-bis(4-nitrophenyl)triazenide salts as antitubercular compounds
Eveline Torfs, Jure Vajs, Maiíra Bidart de Macedo, Freya Cools, Bieke Vanhoutte, Yury Gorbanev, Annemie Bogaerts, Luc Verschaeve, Guy Caljon, Louis Maes, Peter Delputte, Paul Cos, Janez Košmrlj and Davie Cappoen
2017
Design, Syntheses, and in vitro Evaluation of new Fluorine-18 Radiolabeled tau-Labeling Molecular Probes
Luka Rejc, Lojze Šmid, Vladimir Kepe, Črt Podlipnik, Amalija Golobič, Mara Bresjanac, Jorge R. Barrio, Andrej Petrič and Janez Košmrlj
Diaryltriazenes as Antibacterial Agents Against Methicillin Resistant Staphylococcus aureus (MRSA) and Mycobacterium smegmatis
Jure Vajs, Conor Proud, Anamaria Brozovic, Martin Gazvoda, Adrian Lloyd, David I. Roper, Maja Osmak, Janez Košmrlj and Christopher G. Dowson
Synthesis of 1,4-Benzodiazepine-2,5-diones by Base Promoted Ring Expansion of 3-Aminoquinoline-2,4-diones
Filip Křemen, Martin Gazvoda, Stanislav Kafka, Karel Proisl, Anna Srholcová, Antonín Klásek, Damijana Urankar and Janez Košmrlj
Design, synthesis and antitubercular potency of 4-hydroxyquinolin-2(1H)-ones
Maíra B. de Macedo, Roman Kimmel, Damijana Urankar, Martin Gazvoda, Antonio Peixoto, Freya Cools, Eveline Torfs, Luc Verschaeve, Emerson Silva Lima, Antonín Lyčka, David Milićević, Antonín Klásek, Paul Cos, Stanislav Kafka, Janez Košmrlj and Davie Cappoen
Synthesis and X-ray Structural Analysis of the Ruthenium(III) Complex Na[trans-RuCl4(DMSO) (PyrDiaz)], the Diazene Derivative of Antitumor NAMI-Pyr
Jure Vajs, Andrej Pevec, Martin Gazvoda, Damijana Urankar, Evgeny Goreshnik, Slovenko Polanc and Janez Košmrlj
Chemistry and Applications of 4-Hydroxyquinolin-2-one and Quinoline-2,4-dione–Based Compounds
Karel Proisl, Stanislav Kafka and Janez Košmrlj
2016
A mesoionic bis(Py-tzNHC) palladium(II) complex catalyses ‘‘green’’ Sonogashira reaction through an unprecedented mechanism
Martin Gazvoda, Miha Virant, Andrej Pevec, Damijana Urankar, Aljoša Bolje, Marijan Kočevar and Janez Košmrlj
The “Fully Catalytic System” in Mitsunobu Reaction Has Not Been Realized Yet
Daisuke Hirose, Martin Gazvoda, Janez Košmrlj and Tsuyoshi
Org. Lett. 2016, 18, 4036–4039
Listed among the journal's top "20 most read articles in August and September 2016"
Advances and mechanistic insight on the catalytic Mitsunobu reaction using recyclable azo reagents
Daisuke Hirose, Martin Gazvoda, Janez Košmrlj and Tsuyoshi
Ruthenium Azocarboxamide Half-Sandwich Complexes: Influence of the Coordination Mode on the Electronic Structure and Activity in Base-Free Transfer Hydrogenation Catalysis
Michael G. Sommer, Sofiya Marinova, Michael J. Krafft, Damijana Urankar, David Schweinfurth, Martina Bubrin, Janez Košmrlj and Biprajit Sarkar
RuII, IrIII and OsII mesoionic carbene complexes: efficient catalysts for transfer hydrogenation of selected functionalities
Aljoša Bolje, Stephan Hohloch, Janez Košmrlj and Biprajit Sarkar
Regioselective Hydrolysis and Transesterification of Dimethyl 3-Benzamidophthalates Assisted by a Neighboring Amide Group
Marko Krivec, Franc Perdih, Janez Košmrlj and Marijan Kočevar
Discovery of ‘click’ 1,2,3-triazolium salt as potential anticancer drugs
Ivana Steiner, Nikolina Stojanović, Aljoša. Bolje, Anamaria Brozovic, Denis Polančec, Andreja Ambriović-Ristov, Marijana Radić Stojković, Ivo Piantanida, Domagoj Eljuga, Janez Košmrlj and Maja Osmak